DIM Complex Diindolylmethane with Cofactors

60 CAPS Product No. 00612

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Diindolylmethane, also known as DIM, is a gastric metabolite of indole compounds found in cruciferous vegetables. DIM promotes healthy estrogen metabolism by helping to breakdown estrogens in the body, shifting the estrogen balance towards the formation of beneficial metabolites and away from harmful ones. This unique formula contains therapeutic dosages of Diindolylmethane (DIM) and its cofactors—a full array of nutrients that work synergistically to support normal estrogen ratios.*

  • Nourishes methylation processes for healthy metabolism of estrogen*
  • Protects estrogen and its metabolites from oxidative stress*
  • Provides nutrients to support the excretion of estrogen metabolites*


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

DIM Complex: Diindolylmethane with Cofactors


Product Code: 00612        Capsules per Bottle: 60


Each size 0 vegetarian cellulose capsule contains:


Vitamin C (as Ascorbic Acid)

120 mg

Vitamin E (40 IU as d-Alpha Tocopheryl Acid Succinate)

27 mg

Vitamin B-6 (as Pyridoxine HCl)

5 mg

Folate (200 mcg as L-5-Methylfolate, glucosamine salt)

333 mcg DFE

Vitamin B-12 (as Methylcobalamin)

200 mcg

Diindolylmethane (DIM)

100 mg

NAC (as N-Acetyl-Cysteine)

100 mg

Lemon Bioflavonoids

100 mg


100 mg

  Other ingredient: L-Leucine. Natural vitamin E is derived from soy oil.


Description: DIM Complex contains a unique combination of ingredients to provide nutritional support for optimal estrogen metabolism. Diindolylmethane (DIM) is a gastric metabolite of indole compounds found in cruciferous vegetables. DIM is the most active indole derivative for promoting healthy estrogen balance.


Uses: DIM supports breast health, prostate and cervical health. By increasing the ratio of formation of beneficial 2-hydroxyesterone (2-OH) to harmful estrogen metabolites 16-alpha-hydroxyesterone (16a-OH) and 4-hydroxyesterone (4-OH), DIM aids in shifting the estrogen balance to 2-OH and protects against the effects of estrogen dominance.

DIM Complex contains cofactors that work synergistically to support normal estrogen ratios.

Vitamin E, Vitamin C, NAC and lemon bioflavonoids are powerful antioxidants that reduce the oxidation of estrogen metabolites into reactive quinones. The B vitamins methylfolate, B-12 (methylcobalamin) and B-6 are important for estrogen detoxification through methylation. Calcium-D-Glucarate aids in detoxification, binding with estrogen to facilitate its elimination from the body. 


Source Materials: DIM, Pyridoxine HCl, L-5-Methylfolate, glucosamine salt (Quatrefolic®), NAC, and calcium-d-glucarate are made by chemical synthesis. Methylcobalamin is a product of fermentation. Ascorbic acid is derived from corm sorbitol. Vitamin E is derived from purified soy oil (PCR negative). Leucine is derived by sugar fermentation. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan.


Allergens: According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts. Refined soy oil is not considered an allergen.


Recommendations: One to two (1-2) capsules daily, or as directed by a healthcare professional.


Precautions: DIM Complex is usually well tolerated. Side-effects may include gastrointestinal upset and headaches. Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

DIM Complex Diindolylmethane with Cofactors
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