5-HTP (5-Hydroxytryptophan)

60 CAPS | 50 MG Product No. 00100

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5-HTP (5-Hydroxytryptophan)

5-HTP plays a role in both sleep regulation and mood balance. 5-HTP is a precursor for serotonin, which can then be converted to melatonin (the hormone that helps us fall and stay asleep). However, 5-HTP bypasses the light-triggering system that regulates the release of melatonin, increasing both serotonin and melatonin release, regardless of light or time of day. Serotonin has a calming effect on brain chemistry, and may help to ease anxiety. Serotonin also plays an important role in many other bodily functions, including digestion, appetite, and pain perception. Our 5-HTP is naturally derived from the seeds of the African plant Griffonia simplicifolia and is combined with activated vitamin B-6 as active P-5-P, an important cofactor in serotonin metabolism. Consult with your physician if using SSRI’s. *

• Provides important precursor of serotonin and melatonin*

• Nourishes proper gut function*

• Supports healthy mood and sleep*

*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

5-HTP 50 mg


Product Codes: 00100         Capsules per Bottle: 60


Each size 2 vegetarian cellulose capsule contains:

Vitamin B-6 (as Pyridoxal 5 Phosphate)

3 mg


50 mg


220 mg


Description: 5-HTP is a metabolite of L-tryptophan and a precursor of serotonin and melatonin. Our 5-HTP is naturally derived from the seeds of the African plant, Griffonia simplicifolia, and is combined with activated vitamin B-6 (P5P), an important cofactor in serotonin metabolism.


Uses: 5-HTP supports healthy serotonin levels. Serotonin is an important neurotransmitter that plays a role in mood, sleep, anxiety, appetite, pain sensation, and gut health. Clinical trials indicate that 5-HTP provides support for normal moods and emotional well-being.

 5-HTP may moderate appetite and food cravings, and two weight-loss studies recorded significant results compared to placebo. Serotonin is also found in high concentrations in the gut where it regulates gastrointestinal motility.

5-HTP may moderate cranial blood vessel function to promote cranial comfort.

Glycine, an inhibitory neurotransmitter in the central nervous system, can have a calming effect.

Vitamin B-6 is essential for reactions involving the metabolism of amino acids, including the conversion of 5-HTP to serotonin.


Source Materials: 5-HTP is extracted from Griffonia simplicifolia seeds. P5P and glycine are synthetic. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and there is no detectable GM material present.


Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.


Recommendations: Use as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.



  1. Ursin, Reidun. "Serotonin and sleep." Sleep medicine reviews 6.1 (2002): 55-67.

  2. Cho, Suk H., and Lynn Perkes. "Methods and materials for treating depression and mood disorder." U.S. Patent No. 6,068,846. 30 May 2000.

  3. Ioannou, Stephanos, and Adrian L. Williams. "Preliminary fMRI findings concerning the influence of 5‐HTP on food selection." Brain and behavior 7.1 (2017): e00594.

  4. Ito, Susumu. "GABA and glycine in the developing brain." The Journal of Physiological Sciences 66.5 (2016): 375-379.


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

5-HTP (5-Hydroxytryptophan)
60 Capsules
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