Pantothenic Acid

100 CAPS | 500 MG Product No. 00636

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Pantothenic Acid (vitamin B-5) is a component of coenzyme A, which plays an important role in the utilization of fats and carbohydrates in energy metabolism, detoxification, and synthesis of folate derivatives, hormones, and vitamins A and D. Pantothenic Acid (as Calcium D-Pantothenate) supports adrenal function and is often used as part of an adrenal health protocol.*

  • Supports adrenal function*
  • Nourishes production of acetylcholine*
  • Promotes cellular energy production*


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

        Pantothenic Acid


Product Code: 00636/00638     Capsules per Bottle: 100/250


Each size 00 vegetarian cellulose capsule contains:


Pantothenic Acid (as Calcium D-Pantothenate)

500 mg

Other ingredient: L-leucine


Description: Pantothenic acid (vitamin B5) is a precursor in the synthesis of coenzyme A, which plays an essential role in many biochemical reactions that sustain life [1]. Most plants and microorganisms accomplish biosynthesis of pantothenic acid by enzymatically combining pantoic acid with [beta]-alanine. Humans lack the enzyme for this synthetic step, and so we are unable to synthesize pantothenic acid [2]. Pantothenic acid (as calcium D-pantothenate) is essential for adrenal function and is often used as part of an adrenal health protocol [1].

Uses: Coenzyme A, a product of pantothenic acid, and its acyl derivatives are required for the release of cellular energy sources from dietary fats, carbohydrates and protein, as well as energy metabolism, and fatty acid β-oxidation. Coenzyme A is required for synthesis of folate derivatives, hormones, essential fatty acids, cholesterol, steroid hormones, vitamins A and D, and the neurotransmitter acetylcholine. Coenzyme A derivatives are also required for the synthesis of melatonin, and heme, a component of hemoglobin. Additionally, the metabolism of a number of drugs and toxins by the liver require coenzyme A [1].

One of the most consistent findings in pantothenic acid research has been its essential role in the functionality of the adrenal glands. In early pantothenic acid deficiency, the adrenal gland hypertrophies. The adrenal cortex becomes enlarged and ketosteroids progressively decline in the zona reticularis and fasciculata. The eventual result of deficiency is adrenal hypofunction, with an inability to respond appropriately to stress. If pantothenic acid is supplied early enough after deficiency occurs, the response to stress can be improved and morphological changes to the adrenals can be reversed [2].

Clinical studies suggest that pantothenic acid may promote skin cell proliferation, anti-inflammatory action, and tissue repair, implicating pantothenic acid as a promising, potential aid in the process of wound healing [3].

Source Materials: Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.

Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.

Recommendations: Use as directed by a healthcare professional.

Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.


  1. Bauerly K, Rucker RB. Pantothenic acid. In: Zempleni J, Rucker RB, McCormick DB, Suttie JW, eds. Handbook of vitamins. 4th ed. Boca Raton: CRC Press; 2007:289-314.
  1. Kelly, Gregory S. "Pantothenic acid." Altern Med Rev 16.3 (2011): 263-74.
  1. Wiederholt T, Heise R, Skazik C, et al. Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. Exp Dermatol. 2009;18(11):969-978.  (PubMed)


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Pantothenic Acid
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