Product Code: 00439 Capsules per Bottle: 180
Each size 00 vegetarian cellulose capsule contains:
Vitamin C (as Ascorbyl Palmitate)
Magnesium (as Magnesium Glycinate)
Magnesium is an essential mineral with a wide range of biological functions, yet the majority of the population does not get enough dietary magnesium to meet daily requirements. Magnesium makes up the center of every ATP (energy) molecule in the body, but also helps in muscular relaxation. Magnesium glycinate is the most absorbable form of magnesium and helps support healthy muscle, nerve, and heart function, without the laxative effect some people experience from magnesium citrate.
What is Magnesium Glycinate?
Magnesium is an essential mineral, meaning it is needed by, yet not made within the body. Unfortunately, three-quarters of Americans are also estimated to be deficient in magnesium .
Magnesium makes up the center of every ATP (energy) molecule in the body and works as a cofactor in over 300 enzymatic reactions in the body . Taking magnesium before bed can help stave off restless leg syndrome  and aid in the regularity of bowel movements without causing diarrhea .
Magnesium glycinate is a gentle form for individuals who are sensitive to magnesium citrate, as it is less likely to cause a laxative effect. Glycine is considered a relaxing neurotransmitter and may enhance magnesium’s natural calming properties. This makes it an excellent choice in a supplement for those who want to promote mental calm, relaxation, and good quality sleep.
How does Magnesium Glycinate Work?
Magnesium is a cofactor in more than 300 enzymatic reactions within the body; and thus, it is essential for many crucial physiological functions, such as heart rhythm, vascular tone, nerve function, muscle contraction, and relaxation . Magnesium influences vascular tone and reactivity through regulation of cell membrane sodium pump activity, which in turn affects sodium-potassium transport across cell membranes . Magnesium-dependent membrane transport affects nerve signaling, muscle contraction, and normal heart rhythm, as well as healthy glucose metabolism.
As a cofactor in reactions needed for energy production, magnesium aids in several processes leading to the metabolism of carbohydrates and fats. On top of this, ATP, the molecule that provides energy for nearly all metabolic functions, exists primarily as a complex involving magnesium .
Magnesium is also involved in the utilization of calcium, phosphorus, sodium, and potassium, the synthesis of DNA, RNA, proteins, and glutathione, the body’s “master antioxidant” . The growth and maintenance of your bone structure and mineralization are also magnesium-dependent .
In this particular form of magnesium supplement, magnesium is bound to glycine, a non-essential amino acid involved in protein synthesis and transmission of chemical signals in the brain. Glycine has been shown to shorten the time it takes to get to sleep as well as improve sleep quality due to its calming effect on the central nervous system . Outside of its role as a neurotransmitter, glycine is also a rate-limiting glutathione precursor , contributes to detoxification pathways in the body , is a major component in the structure of collagen and cartilage , and aids in muscle and bone health [8,10].
What are the Suggested Uses for Magnesium Glycinate?
- Balance a low magnesium diet - this is a highly absorbable form of this essential mineral, especially for those with gastrointestinal sensitivity.
- Support a calm mood and healthy sleep - both magnesium and its bound glycine are known to promote a sense of calm and improve sleep.
- Muscle comfort
Source Materials: Magnesium is a mined mineral. Glycine is synthetic. Ascorbyl palmitate is derived from corn sorbitol and palm oil.
Allergens: According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.
Recommendations: Use as directed by a healthcare professional.
Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.
- World Health Organization. Calcium and Magnesium in Drinking Water: Public health significance. Geneva: World Health Organization Press; 2009.
- Wilhelm Jahnen-Dechent, Markus Ketteler; Magnesium basics, Clinical Kidney Journal, Volume 5, Issue Suppl_1, 1 February 2012, Pages i3–i14, https://doi.org/10.1093/ndtplus/sfr163
- Hornyak, Magdolna, et al. "Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study." Sleep 21.5 (1998): 501-505.
- NIH. “Magnesium Fact Sheet for Health Professionals”. NIH Office of Dietary Supplements. Accessed Sept 5, 2019. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/#en2
- Sun Ha Jee, Edgar R Miller, Eliseo Guallar, Vikesh K Singh, Lawrence J Appel, Michael J Klag; The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials, American Journal of Hypertension, Volume 15, Issue 8, 1 August 2002, Pages 691–696, https://doi.org/10.1016/S0895-7061(02)02964-3
- Higdon, Jane. “Magnesium”. Linus Pauling Institute. Last reviewed February 2019. https://lpi.oregonstate.edu/mic/minerals/magnesium#function
* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.