­

Product Code: 00521     Capsules per Bottle: 120       Servings per Bottle: 60

Each serving of 2 size 00 vegetarian cellulose capsules contains:

Other ingredients: vegetarian cellulose capsule, L-leucine. Vitamin D derived from lanolin. Vitamin E is derived from soy oil.

What is Basic Maintenance^®?

Basic Maintenance^® is a multivitamin/mineral supplement designed to be taken daily, packed with a full complement of clinical-strength vitamins and minerals essential for organ function and protection. It contains L-methylfolate, the only form of folate with the ability to cross the blood-brain barrier, activated forms of B vitamins, vitamin D-3, and a comprehensive list of high-quality nutrient minerals, making it a valuable component of your daily nutritional regimen.

How Does Basic Maintenance^® Work?

Basic Maintenance^® contains a variety of antioxidants, which help to neutralize and repair damage from oxidative stress. Nutrient antioxidant deficiency is a known cause of numerous chronic and degenerative pathologies [1]. Vitamins C and E work synergistically against free radicals. Alpha-tocopherol, the most bioactive form of vitamin E is a fat-soluble vitamin and potent antioxidant. Due to its fat-solubility, α-tocopherol protects cell membranes from oxidative damage and lipid peroxidation [1]. Vitamin C, also known as ascorbic acid, is a water-soluble vitamin and is essential for collagen, carnitine, and neurotransmitter biosynthesis. Beta-carotene (vitamin A) is also a fat-soluble antioxidant. It is also known as a carotenoid and is converted to retinol, an essential nutrient for vision [1].

Vitamin D-3, cholecalciferol, is the form of vitamin D that our bodies make naturally in response to sunlight and is necessary for the maintenance of bone health and calcium homeostasis [2]. Unfortunately, vitamin D deficiency is a common problem as research on skin health has discouraged many people from exposing their skin to the sun. Vitamin D deficiency is linked with osteoporotic bone loss, increased bone fractures, autoimmune disease, and neurodegenerative disorders [3]. 

Vitamin K aids in the maintenance of healthy bones by regulating calcium uptake in bone tissue, increasing new bone formation, and reducing bone resorption [4]. Zinc, copper, manganese, and boron also support bone mineralization [5].

Selenium (Se) is a trace mineral that forms the active site of several antioxidant enzymes and is a known immunomodulator, along with vitamins A and D. Selenium is also necessary for proper thyroid function [1]. Iodine is also an essential mineral, particularly related to thyroid health, as it is a necessary element in the synthesis of thyroid hormone [6].

B vitamins contained in this supplement blend; thiamine, riboflavin, niacinamide, B-6, biotin, pantothenic acid, folate, and B-12, are commonly associated with energy production, nervous system maintenance, and cardiovascular health. Thiamine, riboflavin, niacinamide, B-6, biotin, and pantothenic acid are cofactors for enzymes needed for cellular energy production through the metabolism of proteins, carbohydrates, and fats. Thiamine, folate, B-12 are involved in the development of neurons and neurotransmitter synthesis [7]. Methylfolate and B-6 are required for homocysteine metabolism and have been linked to mood improvement [8].

What are the Suggested Uses for Basic Maintenance^®?

• A convenient daily multivitamin/mineral to fulfill nutritional needs where diet and lifestyle fall short.
• Provides activated forms of B-vitamins for maximum efficiency, regardless of MTHFR gene status.

Source Materials: Vitamin A palmitate, beta carotene, vitamin K-1, thiamine mononitrate, niacinamide, pyridoxine HCl, pyridoxal 5 phosphate, L-methylfolate, biotin, and pantothenic acid: synthetic. Ascorbic acid: corn sorbitol. Vitamin D3: lanolin from sheep’s wool. Vitamin E succinate: purified soy oil. Vitamin K-2 M7: soy fermentation (soy removed). Riboflavin 5 phosphate and methylcobalamin: dextrose fermentation. Mineral are mined. Chelating agents include: glycine (synthetic), citric acid (corn fermentation), methionine (synthetic), glucuronic acid (synthetic). Cellulose for capsules is derived from softwood tree pulp.

Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.

Recommendations: Use as directed by a healthcare professional.

Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.

References:

1. Pham-Huy, Lien Ai, Hua He, and Chuong Pham-Huy. "Free radicals, antioxidants in disease and health." International journal of biomedical science: IJBS 4.2 (2008): 89.
2. Armas, Laura AG, Bruce W. Hollis, and Robert P. Heaney. "Vitamin D2 is much less effective than vitamin D3 in humans." The Journal of Clinical Endocrinology & Metabolism89.11 (2004): 5387-5391.
3. Tang, Benjamin MP, et al. "Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis." The Lancet 370.9588 (2007): 657-666.
4. Kalkwarf, Heidi J., et al. "Vitamin K, bone turnover, and bone mass in girls." The American journal of clinical nutrition 80.4 (2004): 1075-1080.
5. Reid, Ian R., Mark J. Bolland, and Andrew Grey. "Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis." The Lancet 383.9912 (2014): 146-155.
6. Markou, K., et al. "Iodine-induced hypothyroidism." Thyroid11.5 (2001): 501-510.
7. Selhub, Jacob, et al. "B vitamins, homocysteine, and neurocognitive function in the elderly–." The American journal of clinical nutrition 71.2 (2000): 614S-620S.
8. Bottiglieri, Teodoro, et al. "Homocysteine, folate, methylation, and monoamine metabolism in depression." Journal of Neurology, Neurosurgery & Psychiatry 69.2 (2000): 228-232.