60 CAPS | 500 MG Product No. 00161

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Although the body can convert L-Carnitine to Acetyl-L-Carnitine and vice versa, different forms of carnitine are effective for supporting different functions. L-Carnitine is essential for transporting long-chain fatty acids across the mitochondrial membrane for subsequent fat breakdown and energy generation. The heart gets 70% of its energy from fat breakdown. Because of its role in energy generation, L-carnitine has a broad array of health benefits including weight management, recovery after exercise, cardiovascular health, male fertility, and healthy aging.*

  • Supports normal fat metabolism*
  • Aids in exercise recovery*
  • Supports cardiovascular health*


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

L-Carnitine 500 mg


Product Code: 00161             Capsules per Bottle: 60


Each size 00 vegetarian cellulose capsule contains:


L-Carnitine (as 746 mg L-Carnitine Tartrate)

500 mg


Description: Although the body can convert L-carnitine to acetyl-L-carnitine and vice versa, different forms of carnitine are effective for supporting different functions. L-Carnitine is essential for transporting long-chain fatty acids across the mitochondrial membrane for subsequent fat breakdown and energy generation [1]. L-Carnitine also shuttles short chain fatty acids from inside the mitochondria to the cytosol. Therefore, L-carnitine is, in part, responsible for maintaining energy metabolism throughout the body [1].


Uses:  L-Carnitine is especially relevant to cardiovascular energy metabolism, as the heart gets 70% of its energy from fat breakdown and free fatty acids are the preferred energy substrate for myocardial oxidative metabolism [2]. Myocardial carnitine levels are quickly diminished during ischemic events, and exogenous supplementation with L-carnitine has been shown to replenish depleted myocardial carnitine levels for efficient cardiac metabolism and left ventricular function [2].


Supplementation with L-carnitine has also been linked to improvements in measures of evoked muscular potential [3]. While a great deal of research has been dedicated to carnitine supplementation for enhanced lipid oxidation, spare muscle glycogen, and improved exercise performance, the most significant benefits of L-carnitine, in terms of performance, have been documented in populations with certain existing health conditions, particularly those with various dimensions of cardiovascular disease [3, 4]. The muscular benefits of this supplement for the general, healthy population appear to be related to the recovery process after exercise [3]. L-Carnitine has been shown to mediate the markers of purine catabolism, reduce tissue damage, and facilitate the overall process of recovery [3]. The positive effects of L-carnitine in recovery from stress are thought to act via a cell/tissue-related mechanism, through which oxygen availability is enhanced, and hypoxic stress, free radical formation, membrane disruption, and muscle soreness are reduced [4].


Because of its role in energy generation, L-carnitine has shown a broad array of other health benefits including weight management. Scientific investigations conclude that L-carnitine may decrease fat deposition in favor of protein deposition and improve utilization of dietary fat [1]. Additionally, increased fat oxidation observed after L-carnitine supplementation is not accompanied by any observed protein catabolism [1], indicating a synergistic role for this nutrient in a weight management plan that includes regular exercise.


L-carnitine supplementation has also been shown to support male fertility [5,6]. Part of the physiological role of the epididymis is the epithelial secretion of relatively high levels of carnitines for mitochondrial beta-oxidation of long-chain fatty acids (and subsequent energy metabolism) within spermatozoa [5]. By providing readily available energy for use by spermatozoa, and thus positively affecting sperm motility, maturation and the spermatogenic process, a key role in sperm quality is strongly suggested for L-carnitine. L-Carnitine also has a protective effect on DNA and membranes against damage induced by free oxygen radicals [5].



The multi-faced antioxidant effects of L-carnitine also demonstrate value for this supplement in healthy aging [7]. Additionally, clinical studies show promising results related to improved cognitive function with L-carnitine supplementation [8].


Source Materials: L-carnitine tartrate is made by chemical synthesis. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.


Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, fish, shellfish, peanuts, tree nuts.


Recommendations: Use as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.



  1. Wutzke, Klaus D., and Henrik Lorenz. "The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects." Metabolism-Clinical and Experimental 53.8 (2004): 1002-1006.
  2. DiNicolantonio, James J., et al. "L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis." Mayo Clinic Proceedings. Vol. 88. No. 6. Elsevier, 2013.
  3. Kraemer, William J., Jeff S. Volek, and Courtenay Dunn-Lewis. "L-carnitine supplementation: influence upon physiological function." Current sports medicine reports 7.4 (2008): 218-223.
  4. Volek, Jeff S., et al. "L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress."American Journal of Physiology-Endocrinology and Metabolism 282.2 (2002): E474-E482.
  5. Lenzi, Andrea, et al. "Use of carnitine therapy in selected cases of male factor infertility: a double-blind crossover trial."Fertility and sterility 79.2 (2003): 292-300.
  6. Zhou, Xin, Fang Liu, and Suo-Di Zhai. "Effect of L-carnitine and/or L-acetyl-carnitine in nutrition treatment for male infertility: a systematic review." Asia Pacific journal of clinical nutrition 16.S1 (2007): 383-390.
  7. Gülcin, ─░lhami. "Antioxidant and antiradical activities of L-carnitine." Life sciences 78.8 (2006): 803-811.
  8. Montgomery, Stuart A., L. J. Thal, and R. Amrein. "Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease."International Clinical Psychopharmacology 18.2 (2003): 61-71.


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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