Product Code: 00123 Capsules per Bottle: 120
Each size 00 vegetarian cellulose capsule contains:
Description: This workhorse nutrient performs numerous vital functions, including supporting the body’s normal wound healing and the secretion of key hormones such as insulin and glucagon. L-Arginine is a valuable precursor to nitric oxide which promotes vasodilation and cardiovascular health. It also helps maintain normal systolic and diastolic blood pressure and total and LDL cholesterol.
What is L-Arginine?
Though arginine is considered a nonessential amino acid, it becomes “conditionally essential” as a limiting substrate under stress conditions . This means certain disease states, trauma, or mental stress can stop the body from making enough L-arginine for the body to function effectively. L-arginine is needed to take part in numerous vital functions, including wound healing and the secretion of key hormones such as insulin and glucagon. L-Arginine is also a valuable precursor to nitric oxide which promotes vasodilation and cardiovascular health. It also helps maintain normal systolic and diastolic blood pressure and total and LDL cholesterol.
How does L-Arginine Work?
Nitric oxide, produced from L-arginine in virtually all mammalian cells, plays a role in many cellular processes; one of which is wound healing. Arginine has been shown to promote wound strength and collagen deposition in the healing of acute wounds .
L-Arginine supplementation has also been shown to support cardiovascular function through contributing to processes related to cholesterol balance [2,3], healthy blood flow , normal blood pressure , and the promotion of fat metabolism over fat synthesis [5,6]. Oral supplementation of L-arginine in clinical trials demonstrated an effect of increased exercise-induced blood-flow, mediated by NO . Endothelial production of NO, specifically, is a key element in many of the processes associated with the development of atherosclerosis . Therefore, L-arginine supplementation and the NO production that happens, in turn, is a means to support vascular health in a variety of ways.
L-Arginine also plays an important role in fat metabolism. NO stimulates the oxidation of energy substrates (including fatty acids and glucose) throughout the body . The tissues in which this process takes place include, but are not limited to, fat tissue, the liver, skeletal muscle, and the heart . Dietary arginine supplementation may also increase insulin sensitivity and amplify its signaling mechanisms on net protein synthesis . Arginine supplementation may play a role in the use of dietary energy to favor muscle-building over fat synthesis in adults .
What are the Suggested Uses for L-Arginine?
Supports healthy production of nitric oxide (NO), which in turn contributes to:
- Wound healing
- Healthy blood flow and cardiovascular health
- Regulation of fat metabolism and protein synthesis
Source Materials: Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.
Allergens: According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, fish, shellfish, peanuts, tree nuts.
Recommendations: Use as directed by a healthcare professional.
Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.
- Stechmiller, Joyce K., Beverly Childress, and Linda Cowan. "Arginine supplementation and wound healing." Nutrition in Clinical Practice 20.1 (2005): 52-61.
- Siani, Alfonso, et al. "Blood pressure and metabolic changes during dietary L-arginine supplementation in humans."American journal of hypertension 13.5 (2000): 547-551.
- Preli, Robert B., Karen Potvin Klein, and David M. Herrington. "Vascular effects of dietary L-arginine supplementation."Atherosclerosis 162.1 (2002): 1-15.
- Hambrecht, Rainer, et al. "Correction of endothelial dysfunction in chronic heart failure: additional effects of exercise training and oral L-arginine supplementation."Journal of the American College of Cardiology 35.3 (2000): 706-713.
- Fu, Wenjiang J., et al. "Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats." The Journal of Nutrition 135.4 (2005): 714-721.
- Jobgen, Wenjuan, et al. "Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats." The Journal of nutrition (2008): jn-108.
* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.