100 CAPS | 500 MG Product No. 00140

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The sulfur containing essential amino acid L-methionine is particularly important because it:


  • Assists in the breakdown of fats
  • Aids in maintaining healthy skin tone, well-conditioned hair, and strong nails*
  • Serves as an important antioxidant and detoxifying agent*


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.



Product Code: 00140             Capsules per Bottle: 100


Each size 0 vegetarian cellulose capsule contains:



500 mg



The sulfur-containing essential amino acid, L-methionine, can be a nutritional ally for overall health by aiding the breakdown of fats, detoxification through liver support, antioxidant cellular protection, and production of collagen for strong wound healing and healthy joints, hair, and nails.


What is L-Methionine?

Foods found in the typical adult diet are often limited in their protein value due to a lack of sulfur-containing amino acids such as methionine [1]. L-Methionine (the most efficient form of this amino acid) has antioxidant values, works as a detoxifier, and is considered a protective agent, as it is involved with DNA methylation, synthesis, and repair [2].


How does L-Methionine Work?

S-Adenosyl methionine (SAMe), the first product in the breakdown of methionine, is a key metabolite that regulates the growth, death, and differentiation of liver cells [3]. SAMe can only be synthesized when methionine levels are adequate, and decreased hepatic SAMe biosynthesis is tightly related to all forms of chronic liver injury [3]. Therefore, methionine supplementation may aid in the maintenance and function of a healthy liver.

Likely due to the fact that L-methionine is used to create creatine, which provides muscles with short-term chemical energy, supplementing L-methionine may help patients reach a healthy body weight, and strengthen bone, especially when supplementation is combined with a regular exercise regimen [4].

Dietary methionine is also crucial for the health of the intestine and the immune system (specifically, gut-associated lymphoid tissue) during development and growth, and when the gut is in a state of inflammation [5, 6]. L-Methionine’s role in the metabolism of fatty substances also helps to support blood flow and function of healthy arteries [7].

Last, but not least, L-methionine is essential for the production of collagen, which is a primary component in connective tissues such as skin and cartilage [8]. Healthy tendons, ligaments, bone, hair, and fingernails also require synthesis of significant amounts of collagen. These anti-inflammatory and regenerative effects also support a role for methionine in general wound healing and recovery from injury or disease.


What are the Suggested Uses for L-Methionine?

  • To assist in the breakdown of fats, supporting clear arteries and healthy blood flow. *
  • To support collagen production, which may help to maintain healthy cartilage, efficient wound-healing, youthful skin tone, well-conditioned hair, and strong nails. *
  • To serve as an important antioxidant and detoxifying agent, providing the liver with SAMe substrate for healthy function and regeneration. *


Source Materials: L-Methionine is made by chemical synthesis. Cellulose for capsules is derived from softwood tree pulp. All ingredients are vegan and non-GMO.


Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, fish, shellfish, peanuts, tree nuts.


Recommendations: Use as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement. Because about one-half of methionine is metabolized by the liver, methionine supplementation may be ineffective in alcoholic liver disease [9].



  1. Kies, Constance, Hazel Fox, and Simon Aprahamian. "Comparative value of L-, DL-, and D-methionine supplementation of an oat-based diet for humans." The Journal of nutrition 105.7 (1975): 809-814.
  2. Kune, Gabriel, and Lyndsey Watson. "Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins B6, B12, C, E, selenium, and lycopene."Nutrition and cancer 56.1 (2006): 11-21.
  3. Mato, José M., and Shelly C. Lu. "Role of S‐adenosyl‐L‐methionine in liver health and injury." Hepatology 45.5 (2007): 1306-1312.
  4. Huang, Tsang-Hai, et al. "A Methionine-Restricted Diet and Endurance Exercise Decrease Bone Mass and Extrinsic Strength but Increase Intrinsic Strength in Growing Male Rats–3." The Journal of nutrition 144.5 (2014): 621-630.
  5. Ruth, Megan R., and Catherine J. Field. "The immune modifying effects of amino acids on gut-associated lymphoid tissue." Journal of animal science and biotechnology 4.1 (2013): 27.
  6. Robert F. Grimble; The Effects of Sulfur Amino Acid Intake on Immune Function in Humans, The Journal of Nutrition, Volume 136, Issue 6, 1 June 2006, Pages 1660S–1665S
  7. Novo, Erica, and Maurizio Parola. "Redox mechanisms in hepatic chronic wound healing and fibrogenesis."Fibrogenesis & tissue repair 1.1 (2008): 5.
  8. Rojkind, Marcos, et al. "Connective tissue biomatrix: its isolation and utilization for long-term cultures of normal rat hepatocytes." The Journal of cell biology 87.1 (1980): 255-263.
  9. Charles S Lieber; S-Adenosyl-L-methionine: its role in the treatment of liver disorders, The American Journal of Clinical Nutrition, Volume 76, Issue 5, 1 November 2002, Pages 1183S–1187S.


* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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