Silymarin

60 CAPS | 300 MG Product No. 00304

$26.50
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Our Silymarin capsule provides 300 mg of silymarin from 360 mg of standardized milk thistle (Silybum marianum) extract. Silymarin complex, particularly the silybum component, helps to support the liver through antioxidant activity and stabilization of the cell membranes.* Use with Alpha Lipoic Acid 300 mg for a complete hepatic protective protocol. *
 

  • Supports liver tissue and function*
  • Potent liver protective botanical extract*
  • Aids in liver detoxification processes*

 

*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

     Silymarin

 

Product Codes: 00304/00312     Capsules per Bottle: 60/180

 

Each size 00 vegetarian cellulose capsule contains:

 

Silymarin

(from Milk Thistle Seed Extract, Silybum marianum, standardized to 80% silymarin)

300 mg

Other ingredients: vegetarian cellulose capsule

 

Description: Our Silymarin capsule provides 300 mg of silymarin from 360 mg of standardized milk thistle (Silybum marianum) extract. Silymarin complex, particularly the silybum component, helps to support the liver through antioxidant activity and stabilization of the cell membranes. Use with Alpha Lipoic Acid 300 mg for a complete hepatic protective protocol.

Uses: Silymarin is an extract of the milk thistle (Silybum marianum), the dietary supplement taken most frequently by patients to maintain healthy liver function [1]. Silymarin is an herbal product and no health hazards or side effects have been documented in conjunction with proper administration [2]. Silymarin expresses membrane-stabilizing and antioxidant activities, promotes hepatocyte regeneration, reduces inflammatory reactions, and inhibits fibrogenesis [1]. Silymarin increases protein synthesis in hepatocytes by stimulating RNA polymerase I activity [3]. Silymarin also exhibits fairly specific effects on cell-regulating mechanisms, including, but not limited to, scavenging of reactive oxygen species, indicating a potential for this extract to reduce toxic effects of other drugs [1].

Apoptotic cell death of hepatocytes has emerged as a fundamental component of virtually all acute and chronic liver diseases [4]. Silymarin modulates imbalance between cell survival and apoptosis through interference with the expressions of cell cycle regulators and proteins involved in apoptosis [1].  Antioxidants might aid in the prevention fulminant hepatic failure by interfering with the deadly cascade [4]. Silymarin is also known to increase hepatic glutathione and may also contribute to the antioxidant defense of the liver [3].

Source Materials: Silymarin is extracted from the seeds of milk thistle (Silybum marianum). Cellulose for capsules is derived from softwood tree pulp. All ingredients are non-GMO.

Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, fish, shellfish, peanuts, tree nuts.

Recommendations: Use as directed by a healthcare professional.

Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.

References:

  1. Fehér, János, and Gabriella Lengyel. "Silymarin in the prevention and treatment of liver diseases and primary liver cancer." Current pharmaceutical biotechnology 13.1 (2012): 210-217.
  2. Shaker, E., H. Mahmoud, and S. Mnaa. "Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage." Food and Chemical Toxicology 48.3 (2010): 803-806.
  3. Vargas-Mendoza, Nancy, et al. "Hepatoprotective effect of silymarin." World journal of hepatology 6.3 (2014): 144.
  4. San-Miguel, B., et al. "N-acetyl-cysteine protects liver from apoptotic death in an animal model of fulminant hepatic failure." Apoptosis 11.11 (2006): 1945-1957.

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Silymarin
Standardized Milk Thistle Extract
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