Cal/Mag Plus with Vitamin D and Vitamin K2 MK-7

180 CAPS Product No. 00409

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Peanut and Tree Nut Free Nut Free
Dairy Free Dairy Free
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Cal/Mag Plus provides a complete, balanced supplement to deliver calcium to where it should go in the body. Our unique formula combines calcium and magnesium with two powerful calcium boosters: vitamins D-3 and K-2. Studies have shown that supplementing with magnesium can aide with bone mineralization and muscle relaxation. Vitamin D, most active in the D-3 form, is also essential to maximize absorption of calcium. Vitamin K-2 has been found to promote the synthesis of proteins involved with calcium utilization, helping to keep calcium out of arterial walls and in the muscles and bones where it belongs.*

  • Supports bone health*
  • Promotes healthy nerve and muscle function*
  • Supports cardiovascular health*


* These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Cal/Mag Plus with Vitamin D and Vitamin K2 MK-7


Product Code: 00409          Capsules per Bottle: 180


Each size 00 vegetarian cellulose capsule contains:


Vitamin D-3 (333 IU as Cholecalciferol)

8.3 mcg

Vitamin K (as K2 MK-7)

7.5 mcg

Calcium (as Calcium Citrate/Malate)

167 mg

Magnesium (as Magnesium Citrate/Aspartate)

83 mg

Other ingredients: L-leucine. Vitamin D is derived from lanolin.


Product Description: 

What is Cal/Mag Plus with Vitamin D and K-2 M7?

Cal/Mag Plus with Vitamin D and K-2 M7 is designed to support bone health, cardiovascular health, nerve signaling, and muscle function. Calcium is provided in its highly bioavailable citrate/malate form and magnesium is provided as magnesium citrate/aspartate. Vitamins D-3 and K-2 have been included to maximize the efficiency of calcium absorption and utilization. 

Cal/Mag Plus with Vitamin D and K-2 M7 does not contain the minerals zinc, potassium, and boron found in some of our other Cal/Mag formulas, and so is designed to be taken alongside a multivitamin/mineral that supplies these essentials.


How does Cal/Mag Plus with Vitamin D and K-2 M7 Work?

Calcium is required for the critical metabolic functions of vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Calcium is also necessary for maintaining bone strength (as measured by bone mineral density; BMD). When calcium intake is inadequate, the body starts to break down existing bone to maintain calcium levels in the blood. Osteoporosis occurs when bone is being broken down at a faster rate than it is rebuilt, resulting in decreased BMD [1].

Magnesium is involved in over 300 biochemical reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It contributes to the maintenance of a normal heartbeat and can help to reduce your risk of cardiovascular disease [2]. Magnesium is essential for the absorption of calcium, formation of new bone, and impacts the activity of parathyroid hormone (a regulator of calcium homeostasis) [3]. Sixty percent of the body’s magnesium is stored in bone. Magnesium deficiency can result in reduced BMD as bone will also be broken down to release stored magnesium for other biological functions. 

Vitamin D-3 stimulates the absorption of calcium from the gut. Although vitamin D can be made in the body naturally in response to sunlight, modern indoor lifestyles and awareness of the sun’s effects on skin health have led to low serum vitamin D levels becoming quite common. Vitamin D status is also related to BMD, and supplementation can prevent some bone turnover [4].

Vitamin K-2 M7 works synergistically with vitamin D to stimulate production and activation of osteocalcin, a protein involved in bone mineralization [5]. Osteocalcin is essential for pulling calcium out of the blood and into bone, preventing arterial calcification. Low-dose vitamin K2 M7 supplementation has been shown to decrease bone loss and increase bone strength in postmenopausal women [6].


What are the Suggested Uses for Cal/Mag Plus with Vitamin D and K-2 M7?

  • Support bone health by providing a variety of vitamins and minerals that contribute to the maintenance of healthy bone mineral density.
  • Formula components also support cardiovascular health, nerve signaling, and muscle function.
  • Supplemental vitamin D-3 for those with low serum levels can also help to improve calcium and BMD status. 


Source Materials: Vitamin D3: lanolin from sheep’s wool. Vitamin K2 MK-7: fermentation of soy with Bacillus subtilis natto (all soy removed). Minerals are mined. Chelating agents include: citric acid (corn fermentation), malic acid and aspartic acid (synthetic). Cellulose for capsules is derived from softwood tree pulp. All ingredients are non-GMO.


Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.


Recommendations: Use as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.



  1. Committee to Review Dietary Reference Intakes for Vitamin D and Calcium, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press, 2010.
  2. Del Gobbo,; Circulating and dietary magnesium and risk of cardiovascular disease: a systematic review and meta-analysis of prospective studies. Am J Clin Nutr 2013 Jul; 98(1): 160–173.
  3. Castiglioni, S.; Magnesium and osteoporosis: current state of knowledge and future research directions; Nutrients 2013 (5): 3022-33.
  4. Lips, P., van Schoor NM; The effect of vitamin D on bone and osteoporosis; Best Pract Res Clin Endocrinol Metab 2011 Aug;25(4):585-91.
  5. Weber, P.; Vitamin K and bone health; Nutrition 2001 Oct; 17(10):880-7.
  6. Knapen, MH,; Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women; Osteoporosis Int. 2013 Se;24(90:2499-507.


* These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Cal/Mag Plus with Vitamin D and Vitamin K2 MK-7
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