Betaine Hydrochloride with Pepsin

100 CAPS Product No. 00604

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Betaine Hydrochloride with Pepsin, taken with meals, supports normal digestion. Betaine hydrochloride may lower the pH (increase acidity) of stomach contents for more effective digestion of food and therefore increase the availability and absorption of otherwise bound nutrients. Pepsin is a protease that naturally aids in the breakdown of dietary protein into small peptides for absorption. Betaine hydrochloride should be avoided by those with hyperchlorhydria and stomach cancers. *

  • Optimizes stomach acidity*
  • Promotes proper protein breakdown*
  • May ease symptoms of suboptimal digestion*


*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Betaine Hydrochloride with Pepsin


Product Code: 00604            Capsules per Bottle: 100


Each size 00 vegetarian cellulose capsule contains:


Betaine Hydrochloride

648 mg

Pepsin (1:3,000)

200 mg

Other ingredients: L-leucine. Contains animal pepsin.


Description: Betaine Hydrochloride, taken with meals, supports normal digestion by promoting optimal gastric acidity. Pepsin is a protein-digesting enzyme.


Uses: Low stomach acidity, hypochlorhydria, can occur with aging, several medical conditions, or use of antacids or other drugs to reduce stomach acid such as proton-pump inhibitors. Betaine hydrochloride optimizes stomach acidity which is essential for the solubilization of food particles and the absorption of nutrients. Gastric juices break down proteins and starches prior to the action of intestinal enzymes. Higher stomach pH can lead to nutritional deficiencies due to decreased absorption of iron, electrolytes (calcium, magnesium, zinc) and vitamins. Hypochloridria can also contribute to bacterial overgrowth, stomach discomfort, and reduced absorption of some drugs (1).


Pepsin is a proteolytic enzyme produced in the stomach of humans and other mammals. It is one of the chief digestive enzymes and needed to beak proteins into peptides. Pepsin's proenzyme, pepsinogen, is released by cells in the stomach wall, but requires hydrochloric acid in gastric juice to activate to become pepsin. Betaine Hydrochloride with Pepsin provides both concentrated pepsin and HCl to help activate pepsinogen.


Source Materials: Betaine HCl is made from sugar beets. Pepsin is porcine. L-leucine is derived by fermentation of cane sugar. Cellulose for capsules is derived from softwood tree pulp. All ingredients are non-GMO.


Allergens:  According to information provided by our suppliers, these capsules are free of the eight major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts.


Recommendations: Use as directed by a healthcare professional.


Precautions: Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.



  1. Yago MR, et. al. Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Mol Pharm 2013 Nov 4;10(11):4032-7.


These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Betaine Hydrochloride with Pepsin
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